Martin Jol has made four changes from the side that drew with Arsenal on Saturday.
Chris Baird has stayed in London for personal reasons and has been replaced by Stephen Kelly at right back. Aaron Hughes comes in for Philippe Senderos in centre defence, while Damien Duff comes in for the injured Clint Dempsey and Andy Johnson replaces the ineligible Bryan Ruiz.
FC TWENTE (4-3-3): Mihaylov; Rosales, Tiendalli, Douglas, Wisgerhof; Brama, Landzaat, Fer; Bajrami, de Jong, Chadli. Subs: Marsman, Cornelisse, Bengtsson, Buysse, Janko, John, Gouriye.
FULHAM (4-4-2): Schwarzer; Kelly, J.A. Riise, Hughes, Hangeland; Etuhu, Murphy, Duff, Dembele; Zamora, Johnson. Subs: Etheridge, Senderos, Briggs, Gecov, Kasami, Frei, Sa.